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Functions of Enzymes
by Aftab Ahmed, Ph.D.

Functions of Enzymes

Since they have unique structure, each enzyme is meant to carry out a specific task. Any given enzyme is evolved to fulfill a definite function, and this specificity allows the body to strictly control the use of enzymes. Once activated, an enzyme will perform its specific function until it is "exhausted," or it is inhibited by another enzyme, in which case its activity is curtailed and/or stopped. As researchers have found out after years of painstaking and laborious work, there is a good reason for this control: It prevents bodily processes from spinning out of control, which may be deleterious to health and wellbeing.

Even casually, the specificity of enzymes suggests that there will be particular types. In fact, Nature has "engineered" families of enzymes for specific tasks. One of the most beneficial and abundant classes of enzymes is referred to as proteolytic enzymes. Enzymes in this category have the ability to "nibble" at other proteins, and break them down into smaller chains of amino acids. Hence the name, proteolytic enzymes, which literally means "chewing up proteins."

On the surface, it might appear counterintuitive to degrade proteins in the body. Are proteins not required for optimal cellular function, and do they not afford good health and vibrancy well into the golden years? Indeed, they do! In disease, however, the human body produces proteins that could potentially have injurious effects, and further compromise health if left unattended. It was precisely this goal that Drs. Max Wolf and Helen Benitez set themselves roughly one-half a century ago when they started their quest to find a wholesome, effective and safe alternative for human health and wellbeing. Of course, their objective was to understand how cancer comes about and whether natural alternatives could be designed that will not wreak havoc on the human body as radiation and chemotherapy do. Despite their scientific astuteness, little did Drs. Wolf and Benitez anticipate that their systemic enzymes will afford man immense health benefits, irrespective of whether or not systemic enzymes "cured" cancer.

Drs. Wolf and Benitez, along with Dr. Karl Ransberger, a young biomedical researcher from Germany, tested a large number of enzymes from animal and plant sources. The work was slow, and it progressed in fits and starts, since the researchers had to optimize the conditions to isolate and purify the enzymes. Not only that, they had to struggle to maintain the activity of the enzymes, because the enzymes are notorious for being finicky and unstable. That is, if the enzymes are not handled properly under precisely defined condition, they become inactive. After all, the researchers were working in the 1950s, a time when the basic enzyme technology was still in its infancy, and individual scientists had to rely more on their wits than technology to tweak answers from Nature.

Once Drs. Wolf and Benitez had optimized the conditions necessary to maintain the enzyme activity, they started the next part of their work to combine and evaluate various enzyme formulations in assessing their beneficial effects. These must have been trying times for Drs. Wolf and Benitez. By its very nature, the work was slow, and required almost superhuman patience. After years of dedicated work, they finally experienced the Eureka effect! Their systemic enzymes worked! Perhaps, better than they thought, since beneficial effects of their enzymes were far more varied than they had expected in their wildest expectations.


The Wobenzym Story More...
What are enzymes More...
Benefits of enzymes More...
Functions of enzymes More...

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Note: This material is intended for educational purposes only, and should not be used as a substitute for the advice of a qualified health professional. Statements about the use of any products referred to herein have not been evaluated by the FDA, nor are these products intended to prevent or treat any disease.